Pre-eclampsia is the potentially fatal high blood pressure that affects one in 20 first-time mothers towards the end of pregnancy. Work on mice shows hydrogen sulfide has the ability to block the release of two chemicals that increase blood pressure in the mother and slow the proper development of the placenta. This damage is believed to play a key role in the development of pre-eclampsia and restriction of the baby’s growth. The discovery by researchers at Aston University in Birmingham could lead to a treatment for pregnant women being developed by the end of the decade. It would have to be in pill form because the gas is toxic. Pre-eclampsia can develop into eclampsia, a type of seizure that can be fatal. Condition: Around 20 women and 600 babies die each year from pre-eclampsia (stock image) Around 20 women die each year from conditions linked to high blood pressure including pre-eclampsia, while around 600 babies a year die as a result of pre-eclampsia. The only treatment is to deliver the baby early with an emergency caesarean. Scientists at Aston University found that hydrogen sulfide, a compound known for its offensive rotten egg odour, could reverse damaging changes in the lining of the mother’s blood vessels during early pregnancy. These changes lead to pre-eclampsia complications for the woman such as high blood pressure and damage to her kidneys and liver. But they also affect the function of the placenta and many babies suffer growth restriction that can be life-threatening and cause problems after birth in those who survive. The research suggests women with pre-eclampsia have less hydrogen sulfide in their blood than women with unaffected pregnancies.
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